Proto-Indo-European Roots

Root/Stem: *awo-, *awio-
Meanings:  mother's brother
Cognates (32):
Hellenic Greek aia (ground, motherland)
Italic Latin avus (grandfather)
Celtic Common Celtic *avios (related to grandfather); > 
Old Irish aue, haue (grandson), Irish ó (grandson), Welsh ewythr (mother's brother), Cornish euitor, Breton eontr
Indic
Dardic & Nuristani
Iranian
Anatolian
Tocharian
Armenian Armenian hav, gen. havu (grandfather)
Balkan
Germanic Common Germanic *awón-, *awé-, *awun-; > 
Gothic awó (grandmother), Old Icelandic ái (great grandfather), afi (grandfather), Old English & Old Saxon éam (grandfather), Old Frisian ém, Old High German óheim (mother's brother), Middle Low German óm; 
German Oheim (mother's brother), Dutch oom (grandfather)
Baltic Lithuanian ava (mother's brother's wife), avynas (mother's brother), Old Prussian awis 
Slavic Common Slavic *ujï (mother's brother), > 
Ukrainian vuj, Old Serbian  uika, Bulgarian uiko, Serbo-Croatian ujac, Slovene & Czech & Slovak ujec, Polish wuj (uncle), Lower Sorbian hujk (uncle, cousin), Russian uj (mother's brother)
Notes: The term is rather dark, and its origin and exact meaning are not quite clear yet. It is obvious, however, that it denoted kinship. Most of modern Indo-European languages do not preserve the original complicated system of kinship terms: uncle in English means both 'mother's brother' and 'father's brother', while in Proto-Indo-European there used to be two different words. The same goes for other terms: 'sister's husband', 'son's wife', etc. 
The presence of the initial *H- (laryngeal) is also a question.