Picenes suffered strong Umbrian influence, and their language finally became more Italic than not. Later inscriptions in South Picene show exact Umbrian features. But also it is interesting for its supposed phonological and lexical ties with Illyrian and Thracian languages, as well as some close words with Venetic which are not yet proved. The most considerably hypothesis is that this region was an object of expansion from Balkans, and many different peoples settled here mixing with previos pouplation. But the sounds in South and North Picene have quite a lot differences, and that makes us say these two were of different origin.
In fact, there is still very few information, and we will welcome any additional data about Picene. After Picenes were assimilated by Romans and Umbrians in the 2nd century BC, the language disappeared completely.